Preliminary Evaluation of the Vitros ECi Cardiac Troponin I Assay
نویسندگان
چکیده
منابع مشابه
Analytical performance of the i-STAT cardiac troponin I assay.
BACKGROUND This study determines the analytical characteristics of the i-STAT cardiac troponin I assay (cTnI; i-STAT, Princeton, NJ), a 10-min POC assay, designed to be performed at the bedside. METHODS Three different hospitals participated in a patient specimen and analytical validation study (n=186) for the i-STAT cTnI assay carried out in real time. A total of 186 whole blood specimens (l...
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ve markers of cardiovascular mortality, notably in patients undergoing vascular surgery3, non-cardiac surgery4, traumatic cardiac injury5 or in pregnant women suffering from pre-eclampsia6. Cardiac troponins are thus extensively prescribed in various clinical situations, and their analysis must be carried in appropriate conditions to reach the highest possible accuracy. In France, to reach opti...
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Risk Assessment in Acute Coronary Syndromes, David A. Morrow, Nader Rifai, Marc S. Sabatine, Shake Ayanian, Sabina A. Murphy, James A. de Lemos, Eugene Braunwald, and Christopher P. Cannon ( Department of Medicine and TIMI Study Group, Brigham & Women’s Hospital, 75 Francis St., Boston, MA 02115; 2 Children’s Hospital Medical Center, 300 Longwood Ave., Boston, MA 02115; and 3 Donald W. Reynolds...
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Cardiac troponin is the marker of choice for evaluating myocardial injury (1 ). High-sensitivity assays improve analytical detection limits, thereby allowing concentrations to be measured in the majority of healthy individuals. This capability allows an assessment of biologic variation (BV) to determine what constitutes an important change in the cardiac troponin concentration, a critical metri...
متن کاملHighly sensitive cardiac troponin I assay leads to lowered specificity.
I read with great interest the article of Kavsak et al. (1 ) on the utility of a next-generation high-sensitivity Beckman Coulter cardiac troponin I (cTnI) assay with a 20% CV at 2.95 ng/L. This approach demonstrated a higher diagnostic sensitivity (81% vs 62%) for myocardial injury with a changing pattern of cTnI values, compared with the AccuTnI assay cleared by the US Food and Drug Administr...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2000
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/46.4.560a